IDIOPATHIC PULMONARY FIBROSIS IN THE ERA OF ANTIFIBROTIC THERAPY: SEARCHING FOR NEW OPPORTUNITIES GROUNDED IN EVIDENCE

Idiopathic pulmonary fibrosis in the era of antifibrotic therapy: Searching for new opportunities grounded in evidence

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease that up to now has been MULLEIN associated with a poor prognosis.However, the results of the INPULSIS and ASCEND trials and the approval of nintedanib and pirfenidone have marked the beginning of a new era for IPF patients.Questions remain, however.Should these drugs be use

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Choice of props for courtship dancing in estrildid finches

Abstract Bottle Among the diverse sexual signals used by birds, the possible signaling functions of non-bodily objects during mating/courting displays remain unexplained.It is unclear whether such object-holding gestures are purely ritualistic or serve as an advertisement of an extended phenotype to potential mates.Estrildid finches (family Estrild

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A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer

Despite substantial improvements in the treatment landscape of prostate cancer, the evolution of hormone therapy-resistant and metastatic prostate cancer remains a major cause of cancer-related death globally.The mainstay of treatment for advanced prostate cancer is targeting of androgen receptor signaling, including androgen deprivation therapy pl

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